Tier Ladder
The TrueWriterScore tier ladder assigns every editor to one of four tiers based on the hierarchical gate outcomes (v3.2, pre-registered 2026-05-26).
Tier |
G1 |
Qualifying |
Cell-Based |
Description |
|---|---|---|---|---|
TRUE_WRITER |
PASS |
4/4 |
Yes |
Confirmed Molecular Pen candidate |
PROBABLE_WRITER |
PASS |
4/4 or 3/4 + cell_based |
No / Yes |
Strong evidence, missing cell validation or one gate |
EMERGING_WRITER |
PASS |
1–2 / 4 |
Any |
Partial evidence; further testing needed |
NOT_WRITER |
FAIL or PASS + 0 qualifying |
— |
— |
DSB-maker or insufficient evidence |
Pre-registered outcomes (2026-05-26)
P1 PASS: ISCro4 is the sole TRUE_WRITER among natural editors
P2 PASS: Zero pen-assemble designs are TRUE_WRITER
Universe composition (Step 5)
29 natural editors (all pen-score entries after S_Mature clamp fix)
1,029 computational designs (pen-assemble v0.5.2 catalog)
Total: 1,058 entities
Scorecard summary
Tier |
Count |
|---|---|
TRUE_WRITER |
1 |
PROBABLE_WRITER |
4 |
EMERGING_WRITER |
1,037 |
NOT_WRITER |
16 |