Sensitivity Analysis
Sensitivity analysis evaluated robustness of all tier assignments across an 20,480-combination parameter grid (16x16x16x5 threshold variations).
Grid definition
Parameter |
Range |
N values |
|---|---|---|
G1 threshold (S_DSB) |
0.85-0.99 (step 0.01) |
15 |
G2 threshold (S_Prog) |
0.85-0.99 (step 0.01) |
15 |
G3 threshold (S_Cargo) |
0.80-0.95 (step 0.01) |
16 |
G4 size max (aa) |
600, 750, 900, 1050, 1200 |
5 |
Key findings
ISCro4 robustness = 1.000 - TRUE_WRITER under all 20,480 combinations
Zero boundary cases (robustness < 0.50) - no tier is genuinely ambiguous
4 near-boundary editors (50-80% robustness): Bxb1 (0.5625), eePASSIGE (0.5625), eePASSIGE_v2 (0.5625), phiC31 (0.75)
1,055 / 1,058 entities (99.7%): default tier == modal tier